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Nitroglycerin Glyceryl Trinitrate GTN
We have a recognized expertise in the pre-formulated nitroglycerin production (also called Glyceryl Trinitrate or GTN) for pharmaceutical application thanks to more than 150 years of experience in explosives and energetic chemistry. Our preformulated nitroglycerin drug is used as solid, gel, or liquid forms:
- Adhesive solutions for patches
- Pastes for reservoir patches
- Solutions for Gelatinous capsules
- Spray solution
- Pre-mixes for parenteral products, tablets and capsules
- Gels and ointments
Nitroglycerin drug product is used in various therapeutic areas including:
- Angina pectoris
- Acute Myocardial Infarction
- Severe Hypertension
- Acute Coronary Artery Spasms
- Heart diseases
- Anal fissures and hemorrhoids
Our Nitroglycerin production is GMP certified, and we are holding a manufacturing license according to the German drug law. We have been successfully certified several times by world leading organizations like US FDA, European Medicines Agency and Japanese PMDA.
In addition, we have a strong regulatory affairs assistance to support our customers worldwide.
Beyond the quality aspects, our customers will benefit from our strength in safety, based on our extensive experience in handling explosives according to the German Explosive Acts.
Therapeutic area
- Acute Coronary Artery Spasms
- Acute Myocardial Infarction
- Angina
- Severe Hypertension
Monograph
- Mixtures: Ph. Eur., USP
- Pure GTN: INTERNAL SPEC.
Available grade
- Mixtures: Multiple grades available
- Pure GTN: DNES
Regulatory documentation
- CEP
- EU DMF
- JP DMF
- Mixtures:
- Pure GTN:
- US DMF**
Produced in
LEV
Product Category
Specialty Products
Our center of excellence for energetics chemistry
Nitroglycerin production is located in our facility in Leverkusen in Germany, and we also have a backup nitration plant at the same site for business continuity and that enables us to cover all demands from our customers worldwide.
Nitroglycerin Glyceryl Trinitrate is a product of our 140+ year expertise, and we are today the largest pharma grade producer of nitroglycerin globally.
We have a large number of mixtures available, and are also able to develop new ones if needed. Our product offering and expertise in handling this dangerous good is unparalelled in the pharma industry.
We enable our partners to fully realize their ambitions.
Driven by the curiosity, skills and dedication of over 2,000 employees on three continents, Axplora delivers sustainable, technologically advanced API solutions to improve lives worldwide.