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ADC manufacturing

ADC development brings complex manufacturing and supply chain risks. Secure your antibody–drug conjugate (ADC) program with a partner who understands this complexity. Our clinical and commercial-scale ADC drug substance manufacturing is backed by 20 years of experience and fully integrated payload and bioconjugation expertise.

End-to-end ADC expertise

Secure your supply chain with a partner trusted by 6 out of 14 FDA-approved ADCs. Novasep CDMO simplifies your logistics by co-locating payload and bioconjugation manufacturing at a single site. Backed by 20 years of experience and a track record of >250 cGMP batches delivered, we support commercial success and deliver to tight timelines.

Why choose us?

  • 20+ years of cGMP ADC manufacturing experience.
  • Proven supply chain partner for 6 of 15 FDA-approved ADCs.
  • Co-located payload and conjugation to eliminate transport risk.
  • Specialized handling up to OEB6 (OEL < 30ng/m³) backed by a 100% regulatory inspection track record.
  • A 100% regulatory inspection track record worldwide.
  •  4 dedicated linker-payload workshops (2 clinical, 2 commercial) providing scalable capacity from grams to kilograms

Seamless path from payload to conjugate

We have invested $20M in our bioconjugation and linker-payload suites to smooth the transition from early development to commercial supply. By integrating these steps at our Le Mans center of excellence, we reduce risk and accelerate your timeline.

Explore related services

Learn more about our integrated ADC expertise.

ADC Payloads

Strengthen your program with proven high-containment excellence. As a partner on six FDA-approved ADCs, we bring 20+ years of experience with 300+ cGMP batches to ensure reliable commercial supply.

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Latest updates

FAQs

FAQ – Antibody Drug Conjugates (ADC)

Do you want to learn more about ADC? Axplora is respected as a key contract service provider in the ADC arena with more than 15 years of experience. We provide unique services for the development, fast-track, clinical supply, and commercial cGMP manufacture of ADCs, including the payload linker and the bioconjugation. In this FAQ, our […]

Case study

ADC Payload

Process development and manufacturing of an ADC payload from phase I to commercial Axplora is an expert in ADC Payload manufacturing with over 15 years’ experience and more than 200 clinical and commercial cGMP batches produced. We safely handle compounds with very low OEL, below 30ng/m³/8hrs, and we can produce from 30g to > 1kg […]

Case study

ADC Bioconjugation

Development and cGMP manufacturing of a Phase I clinical candidate Axplora is an expert in ADCs with over 15 years’ experience and more than 200 clinical and commercial cGMP batches produced. We have a multi-scale bioconjugation manufacturing capacity with short-term availability and a fast-track bioconjugation services with seamless transition to clinical supply. A clinical-stage biopharmaceutical […]

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Work with a proven leader in ADC manufacturing.