Search Axplora

Home / Novasep CDMO / Technologies / Solid State Chemistry

Solid state chemistry

Optimize bioavailability and processability with Axplora’s centre of excellence in Gropello for solid state design and analysis. With 100+ projects in polymorphism and co-crystal screening, we deliver consistent physical properties for your API.

Consistency at scale

Our team, led by Dr Davide Bardone, has a proven track record in complex crystallisation processes to improve bioavailability and processability of solid-state APIs. We also develop and scale micronisation processes to achieve the required particle size distribution (PSD), ensuring consistent performance from development through commercial supply.

Why partner with us?

  • Leverage >100 projects of solid state experience.
  • Optimize polymorphism and Particle Size Distribution (PSD) for formulation success.
  • Ensure consistent bioavailability and filtration rates.
  • Scale robust crystallization processes from lab to industrial manufacturing.
  • Benefit from a proven regulatory track record in physical form characterization.

Consistency without compromise

Our solid state expertise ensures consistency and safety when scaling complex reactions. We deliver reliable outcomes for global pharma and biotech partners, supporting programs that require industrial-scale capacity and rigorous quality control.

Explore related technologies

Learn more about our continuous and innovative processes.

Flow Chemistry

Improve safety and selectivity. With 10+ years of experience, we identify optimal parameters and safely run hazardous reactions and extreme temperatures impossible to control in batch mode.

Energetic Chemistry

With over 40 years of expertise, we produce 400+ tons of azides annually using advanced containment systems that drive safe, efficient manufacture and lower costs.

Latest updates

Brochure

Axplora - Accelerate your Early clinical success

Accelerating your early clinical success

Your early-stage program is moving at orbital speed. Your CDMO should too. Early-stage small molecule development is a race against time. Tight clinical timelines, evolving processes, limited resources, and increasing regulatory expectations leave little room for delay. At Axplora, we’ve built an early-phase offering designed to help innovators accelerate their path to the clinic. With […]

Leaflet

Accelerate your API journey with a leading CDMO

Axplora’s flight plan to success When your mission is ambitious, your CDMO partner must be fearless: accelerate your API journey with Axplora – your trusted CDMO co-pilot. From early-phase development to commercial manufacturing, Axplora delivers value, precision, and partnership – helping you navigate complex supply chains, evolving regulations, and demanding timelines with confidence. ✅ Reliable […]

Whitepaper

Dare to use preparative chromatography at industrial scale for your API

Maximise purity, efficiency, and sustainability. Is purification stalling your API journey to market?You’re not alone! Every molecule is a new frontier—with its own complex terrain. But here’s the bold truth: the future belongs to those who dare to imagine better solutions. Preparative chromatography as a powerful purification technology can unlock major benefits for your complex […]

Partner with us today

Secure consistency and scalability with the experts behind >100 solid state projects.