Locations in Europe
Our API sites in Europe
A wide network of 8 sites is available in Europe, in France, Germany and Italy. Axplora offers best-in-class CDMO services for APIs and advanced intermediates from process development to clinical and commercial manufacturing. In addition, we develop, scale-up and manufacture commercial APIs and advanced intermediates for the generic and originator pharmaceutical industry.
Our site in Chasse-sur-Rhône
- Novasep CDMO plant
- Process development, scale-up and manufacturing
- Expertise in combining organic chemistry with advanced purification technologies
Located near Lyon (France), our Chasse-sur-Rhône site offers CDMO services for APIs from clinical supply to commercial manufacturing. The site has an outstanding regulatory track-record, and offers industrial chromatography, low temperature reactions, high pressure hydrogenation, and an extensive toolbox of classical technologies.
Our site in Gropello Cairoli
- Farmabios Plant
- Process development, scale-up and manufacturing
- Specialized in steroids and HPAPI synthesis
- Solid state expertise
- Strong regulatory history
- EcoVadis 2023 GOLD certified
Founded in 1961 and located near Milan (Italy), Gropello Cairoli’s site comprises team of over 200 employees. It is a world leader in steroid chemistry, producing more than 80 APIs and advanced intermediates such as Corticosteroids & Hormones (sterile & non-sterile). It also has great expertise in the scale-up and production of HPAPIs, including cytotoxics, as well as cannabidiol (CBD). The site offers CDMO services and hosts Axplora’s center of excellence in solid state chemistry.
Our site in Leverkusen
- Novasep CDMO plant
- Process development, scale-up and manufacturing
- Expertise in hazardous chemistry
Our custom manufacturing site in Leverkusen, located near Cologne in Germany, was founded more than 150 years ago and is Axplora’s center of excellence for hazardous chemistry. This site is a world leader in providing CDMO services for API, advanced intermediates, fine and agro-chemicals from development to multi-ton scale, using an unparalleled range of energetic reactions such as azide, carbon disulfide, hydrazine chemistries, carbonylation, 02 oxidation, etc, and reactions involving hazardous reagents such as sodium cyanide. It is also a major producer of nitroglycerin-based APIs, supplied in various formulations for the generic market.
Latest inspections:
- National Health Authorities (Manufacturing permit and GMP certificate): 2023
- US FDA: 2018
- PMDA:
- ISO9001 and ISO50001: 2021
Our site in Le Mans
- Novasep CDMO plant
- Process development, scale-up and manufacturing
- ADC manufacturing: payloads, payload-linkers, ADC conjugation and ADC drug product release testing
Conveniently located one hour from Paris by high-speed train, our Le Mans custom manufacturing site benefits from more than 30 years of experience in HPAPIs and industrial chromatography . The site offers to pharmaceutical innovators full CDMO services for the process development, scale-up and commercial production of ADCs. With a state-of-the-art facility, the site provides a full and flexible range of ADC manufacturing services and has hands-on experience on most payload-linker and conjugation platforms.
Our site in Mourenx
- Novasep CDMO plant
- Process development and large-scale manufacturing
- Large scale continuous chromatography
- Purification of omega-3
Located near Pau (South West of France), our Mourenx site has over 40 years of CDMO experience in large scale API manufacturing & benefits from an excellent regulatory track record. The site houses the world’s largest continuous industrial chromatography facilities equipped with total solvent recycling for the multi-ton production of ultra-purified omega-3 APIs such as Icosapent ethyl.
Our site in Pompey
- Novasep CDMO plant
- Process development, scale-up, and manufacturing
- Most versatile contract purification platform in the world for biologics and small molecules
- Best-in-class expertise in purification including chromatography
Located near Nancy (France), this site is Axplora’s center of excellence for chromatography. The site has more than 25 years of experience in CDMO services involving industrial chromatography for the purification of APIs, cGMP intermediates & biomolecules from process development to commercial supply. Key technologies include large scale HPLC, continuous chromatography (SMB), low pressure chromatography, process simulation, and membrane filtration (UF/DF, nanofiltration).
Headquarters and manufacturing site in Raubling
- PharmaZell Plant
- Axplora Group Headquarters
- Electrochemistry and enzymatic reactions
- EcoVadis 2023 SILVER certified
- Five production units on a commercial scale
- Seven production lines
- One pilot plant according to cGMP standard
- Laboratories for customised development and analysis
- Small scale laboratory according to cGMP standard
The Raubling site near Munich (Germany) hosts Axplora’s headquarters in addition to a production facility for generic APIs and CDMO services. It was founded in 1946 with a generic pharmaceutical focus on different therapeutic areas such as anti-inflammatory, gastrointestinal, mucolytic and anti-arrhythmic. A team of over 150 employees is involved in the development, scale-up and manufacture of APIs with customized particle sizes and physical properties. It has a unique experience in operating electro-chemistry and enzymatic reactions at multi-ton scale.
Most recent inspections and audits:
- Government of Upper Bavaria, competent authority (Germany), regularly, 2022
- FDA (US), regular, 2022
- PMDA (JP), 2016
- Regular customer audits
Management Center in Lyon
- Novasep CDMO center
- Support Functions
In addition to our API sites, we have a Management Center in Lyon. It hosts some of the members of Axplora’s Executive Committee, as well as some support functions such as communication, finance and legal. It gathers a team fully committed to support the whole Axplora group.
