Glyceryl Trinitrate

CAS number: 55-63-0

We have a recognized expertise in the pre-formulated nitroglycerin production (also called Glyceryl Trinitrate or GTN) for pharmaceutical application thanks to more than 150 years of experience in explosives and energetic chemistry. Our preformulated nitroglycerin drug is used as solid, gel, or liquid forms:

  • Adhesive solutions for patches
  • Pastes for reservoir patches
  • Solutions for Gelatinous capsules
  • Spray solution
  • Pre-mixes for parenteral products, tablets and capsules
  • Gels and ointments

Nitroglycerin drug product is used in various therapeutic areas including:

  • Angina pectoris
  • Acute Myocardial Infarction
  • Severe Hypertension
  • Acute Coronary Artery Spasms
  • Heart diseases
  • Anal fissures and hemorrhoids

Our Nitroglycerin production is GMP certified, and we are holding a manufacturing license according to the German drug law. We have been successfully certified several times by world leading organizations like US FDA, European Medicines Agency and Japanese PMDA.
In addition, we have a strong regulatory affairs assistance to support our customers worldwide.
Beyond the quality aspects, our customers will benefit from our strength in safety, based on our extensive experience in handling explosives according to the German Explosive Acts.

Our center of excellence for energetics chemistry

Nitroglycerin production is located in our facility in Leverkusen in Germany, and we also have a backup nitration plant at the same site for business continuity and that enables us to cover all demands from our customers worldwide.

Axplora expertise in hazardous chemistry
Axplora expertise in hazardous chemistry

Nitroglycerin Glyceryl Trinitrate is a product of our 140+ year expertise, and we are today the largest pharma grade producer of nitroglycerin globally.

We have a large number of mixtures available, and are also able to develop new ones if needed. Our product offering and expertise in handling this dangerous good is unparalelled in the pharma industry.

  • Therapeutic area Angina
    Acute Myocardial Infarction
    Severe Hypertension
    Acute Coronary Artery Spasms
  • Monograph Pure GTN: INTERNAL SPEC.

    Mixtures: Ph. Eur., USP
  • Available grade Pure GTN: DNES

    Mixtures: Multiple grades available
  • Regulatory documentation Pure GTN:

  • Produced in LEV